Generation of Recombinant Chinese Hamster Ovary Cell Lines by Microinjection
نویسندگان
چکیده
منابع مشابه
Propranolol induced chromosomal aberrations in Chinese hamster ovary cell line
Propranolol (PL), a non-selective beta-blocker, is a cardiovascular drug widely used to treat hypertension. The present study was concerned with assessing the cytogenetic effects of this drug on Chinese hamster ovary (CHO) cell line. MTT assay was then carried out to determine the cytotoxicity index (IC50) of the drug. The IC50 value of PL was 0.43±0.02 mM. To investigate the clastogenic effect...
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ژورنال
عنوان ژورنال: Biotechnology Letters
سال: 2006
ISSN: 0141-5492,1573-6776
DOI: 10.1007/s10529-005-6062-6